Современная фармакологическая промышленность создала уже огромное количество лекарств. Однако, как известно, у нашего организма имеется и, так сказать, «встроенная» система для борьбы с различными патологиями. Система эта носит название «иммунитет». И он способен на многое. Даже если его особенности могут показаться не столь очевидными. К примеру, не так давно группа исследователей из Йельского университета создала вещество, которое перестраивает систему иммунитета таким образом, чтобы последняя уничтожала раковые клетки.

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Оказывается, иммунная система может победить рак. Нужно ей в этом лишь немного помочь
Как справиться с раком?
Как сообщается на сайте университета, исследовательская группа, возглавляемая сотрудниками учебного заведения Акико Ивасаки и Анной Пайл, изучила, может ли синтетическая молекула РНК, разработанная для борьбы с вирусами, также вызвать иммунный ответ против опухолей. Молекула, получившая название Stem Loop RNA 14 (SLR14), была специально разработана для активации гена, который обнаруживает вирусы и другие угрозы в клетках.
Наша идея состоит в том, чтобы имитировать вирусную инфекцию внутри опухоли, обманывая иммунную систему. Это заставит ее обратить внимание на «инфекцию» и уничтожить ее, параллельно уничтожив и опухолевый процесс. — говорит Акико Ивасаки.
Чтобы проверить эту теорию, исследователи провели серию экспериментов. Они ввели SLR14 непосредственно в опухоли у мышей и наблюдали процесс разрушения рака Т-клетками иммунной системы. При этом введение молекулы в одном месте также простимулировало Т-клетки для того, чтобы начать работать и в другой области организма, пораженной онкологией. На страницах нашего портала мы часто пишем о подобного рода изысканиях, поэтому если вам интересна эта тема, то подписывайтесь на наш новостной канал в Телеграм.
Читайте также: Грибы уменьшают риск развития рака простаты
В другом своем эксперименте ученые имитировали метастазирование рака, распространяя опухолевые клетки по всему телу. Ученые ввели их через левый желудочек сердца грызунов, чтобы разнести клетки в как можно большее количество органов. Да, это звучит не совсем гуманно, но иначе проверить гипотезу, к сожалению, просто не получится. Результаты показали, что терапия SLR14 при метастазированных опухолях также оказывается эффективной.
Дальнейшее исследование действия препарата показало, что SLR14 сопоставим по своей эффективности с существующими лекарственными средствами для иммунотерапии рака и может усилить их противоопухолевый ответ. Специалисты Йельского униврситета также обнаружили, что «память» иммунной системы, которая была простимулирована такой терапией, также защищает и от рецидивов опухолевых образований в будущем и даже дает возможность уничтожения рака на ранних стадиях зарождения опухолевого процесса.
Мы должны использовать иммунную систему, чтобы найти опухоли и убить их, прежде чем они станут раковыми. — говорит Анна Пайл.
Следующим шагом в исследовании препарата является тестирование такого метода терапии в качестве самостоятельного. Также ученые хотят проверить его эффективность в сочетании с другими вариантами лечения вроде лучевой или химиотерапии. Помимо этого исследователи также нацелены на проведение опытов с участием людей-добровольцев.
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If no cards come out during a quarante match, then the player must
call, raise, or fold. There are generally three different betting bets in each sport:
win, cover, and half-pay.
Traditionally, the traditional Italian card game, tarantella, was played at
the St Regis Hotel. This specific variant of the game involved a tableau
de quarante where all of the players would sit
at particular places on the warranty row. In this type of
game, there were red and black rooms, together with the winning player being the player who was able to finish
their last five cards before the other players ended theirs.
Today, there are literally hundreds of variations of the
traditional French card game, et noir. In actuality, the most common variation is only a variation on the red and black
rooms. In most versions, there are four suites;
a black package, a reddish suite, plus a blue suite. The players can win by laying down a total of twenty-one free cards, including one card from each of
the four suites. Once all players have lost their cards,
the dealer randomly selects one card from each of the four suites and puts it in the center of
this quarante table.
These days, the term»quarante» means»of or relating to quarantining.» Traditionally, the game was known as»trente et noir» which meant playing cards with names.
It has also been referred to as»trente» and»ne monetaire» from the French speaking world.
Today, it refers only to card games which contain playing cards with titles.
Traditionally, the game was always played between two people seated across a small table; however, in America it’s usually played in a bar or lounge.
Each individual dealt three cards face down, one at a time to one another.
If anyone got rid of one of those three cards, then they had to
switch places with the man who they had dealt with the first card to.
The man who dealt the last card, in turn, then had to get rid of the hand by passing another card
to the person they handed it to.
The»quaint» version of this game is available for people
who want to play something a little more simple. Although
there are variations on the best way to play the game, the basic rules remain the same.
The object stays the same, to form the highest possible hand without having any cards left to spare.
This can be achieved with ease, especially if you
have already mastered the fundamentals of playing the game of blackjack, because
the basic rules of this card game are extremely easy to learn and grasp.
The basic concept of the game of»monte carlo» stays the same, since it’s a simple
game which can be played by almost anyone.
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