Создано лекарство, которое «настраивает» организм на борьбу с раком

Современная фармакологическая промышленность создала уже огромное количество лекарств. Однако, как известно, у нашего организма имеется и, так сказать, «встроенная» система для борьбы с различными патологиями. Система эта носит название «иммунитет». И он способен на многое. Даже если его особенности могут показаться не столь очевидными. К примеру, не так давно группа исследователей из Йельского университета создала вещество, которое перестраивает систему иммунитета таким образом, чтобы последняя уничтожала раковые клетки.

Создано лекарство, которое «настраивает» организм на борьбу с раком

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Оказывается, иммунная система может победить рак. Нужно ей в этом лишь немного помочь

Как справиться с раком?

Как сообщается на сайте университета, исследовательская группа, возглавляемая сотрудниками учебного заведения Акико Ивасаки и Анной Пайл, изучила, может ли синтетическая молекула РНК, разработанная для борьбы с вирусами, также вызвать иммунный ответ против опухолей. Молекула, получившая название Stem Loop RNA 14 (SLR14), была специально разработана для активации гена, который обнаруживает вирусы и другие угрозы в клетках.

Наша идея состоит в том, чтобы имитировать вирусную инфекцию внутри опухоли, обманывая иммунную систему. Это заставит ее обратить внимание на «инфекцию» и уничтожить ее, параллельно уничтожив и опухолевый процесс. — говорит Акико Ивасаки.

Чтобы проверить эту теорию, исследователи провели серию экспериментов. Они ввели SLR14 непосредственно в опухоли у мышей и наблюдали процесс разрушения рака Т-клетками иммунной системы. При этом введение молекулы в одном месте также простимулировало Т-клетки для того, чтобы начать работать и в другой области организма, пораженной онкологией. На страницах нашего портала мы часто пишем о подобного рода изысканиях, поэтому если вам интересна эта тема, то подписывайтесь на наш новостной канал в Телеграм.

Читайте также: Грибы уменьшают риск развития рака простаты

В другом своем эксперименте ученые имитировали метастазирование рака, распространяя опухолевые клетки по всему телу. Ученые ввели их через левый желудочек сердца грызунов, чтобы разнести клетки в как можно большее количество органов. Да, это звучит не совсем гуманно, но иначе проверить гипотезу, к сожалению, просто не получится. Результаты показали, что терапия SLR14 при метастазированных опухолях также оказывается эффективной.

Дальнейшее исследование действия препарата показало, что SLR14 сопоставим по своей эффективности с существующими лекарственными средствами для иммунотерапии рака и может усилить их противоопухолевый ответ. Специалисты Йельского униврситета также обнаружили, что «память» иммунной системы, которая была простимулирована такой терапией, также защищает и от рецидивов опухолевых образований в будущем и даже дает возможность уничтожения рака на ранних стадиях зарождения опухолевого процесса.

Мы должны использовать иммунную систему, чтобы найти опухоли и убить их, прежде чем они станут раковыми. — говорит Анна Пайл.

Следующим шагом в исследовании препарата является тестирование такого метода терапии в качестве самостоятельного. Также ученые хотят проверить его эффективность в сочетании с другими вариантами лечения вроде лучевой или химиотерапии. Помимо этого исследователи также нацелены на проведение опытов с участием людей-добровольцев.

Источник: news-ria.ru
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                                                                                                                                                  Gambling has long been a tabooed subject in many societies;
                                                                                                                                                  in fact, a lot of people consider it to be a kind of gambling.
                                                                                                                                                  However, a lot of people still enjoy the excitement and thrill that come
                                                                                                                                                  along with gambling; therefore, the reason why there are casinos all over the world.

                                                                                                                                                  Betting has even made its way into popular culture, with
                                                                                                                                                  reality shows like»The Weakest Link» where folks play slots.

                                                                                                                                                  Quarantee (black and red ) is probably the most well known type of casino game, and probably
                                                                                                                                                  the one with the maximum level of interest among gamblers.

                                                                                                                                                  It is often compared to a cross between poker and slots, since it requires the participant to place bets based on the cards that come from the quarante deck.

                                                                                                                                                  Even though the specific mechanics of how these bets are made is largely unknown, it’s
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                                                                                                                                                  As well as the cards that come out of this quarante deck, the player must also choose a hand of cards which
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                                                                                                                                                  There are basically two types of bets in quarantine.

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                                                                                                                                                  Traditionally, the traditional Italian card game, tarantella, was played at
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                                                                                                                                                  Today, there are literally hundreds of variations of the
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                                                                                                                                                  the dealer randomly selects one card from each of the four suites and puts it in the center of
                                                                                                                                                  this quarante table.

                                                                                                                                                  These days, the term»quarante» means»of or relating to quarantining.» Traditionally, the game was known as»trente et noir» which meant playing cards with names.
                                                                                                                                                  It has also been referred to as»trente» and»ne monetaire» from the French speaking world.
                                                                                                                                                  Today, it refers only to card games which contain playing cards with titles.

                                                                                                                                                  Traditionally, the game was always played between two people seated across a small table; however, in America it’s usually played in a bar or lounge.
                                                                                                                                                  Each individual dealt three cards face down, one at a time to one another.

                                                                                                                                                  If anyone got rid of one of those three cards, then they had to
                                                                                                                                                  switch places with the man who they had dealt with the first card to.
                                                                                                                                                  The man who dealt the last card, in turn, then had to get rid of the hand by passing another card
                                                                                                                                                  to the person they handed it to.

                                                                                                                                                  The»quaint» version of this game is available for people
                                                                                                                                                  who want to play something a little more simple. Although
                                                                                                                                                  there are variations on the best way to play the game, the basic rules remain the same.
                                                                                                                                                  The object stays the same, to form the highest possible hand without having any cards left to spare.
                                                                                                                                                  This can be achieved with ease, especially if you
                                                                                                                                                  have already mastered the fundamentals of playing the game of blackjack, because
                                                                                                                                                  the basic rules of this card game are extremely easy to learn and grasp.

                                                                                                                                                  The basic concept of the game of»monte carlo» stays the same, since it’s a simple
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